Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya

BACKGROUND: Malarial anaemia is characterized by destruction of malaria infected red blood cells and suppression of erythropoiesis. Interleukin 12 (IL12) significantly boosts erythropoietic responses in murine models of malarial anaemia and decreased IL12 levels are associated with severe malarial a...

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Autors principals: Zhang, Lyna, Prather, Donald, Eng, Jodi Vanden, Crawford, Sara, Kariuki, Simon, ter Kuile, Feiko, Terlouw, Dianne, Nahlen, Bernard, Lal, Altaf A, Slutsker, Laurence, Udhayakumar, Venkatachalam, Shi, Ya Ping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858737/
https://ncbi.nlm.nih.gov/pubmed/20350312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-87
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