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PSD-95 and Calcineurin Control the Sensitivity of NMDA Receptors to Calpain Cleavage in Cortical Neurons
The N-methyl-D-aspartate receptor (NMDAR) is a Ca(2+)-permeable glutamate receptor mediating many neuronal functions under normal and pathological conditions. Ca(2+)-influx via NMDARs activates diverse intracellular targets, including Ca(2+)-dependent protease calpain. Biochemical studies suggest th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858625/ https://ncbi.nlm.nih.gov/pubmed/18445709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.046813 |
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