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Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1
Multiple endocrine neoplasia type 1 (MEN1) is a familial tumor syndrome linked to mutation of the MEN1 gene, which encodes a tumor suppressor, menin. We previously reported that menin upregulates the caspase 8 expression and promotes TNF-α-induced apoptosis. However, it remains unclear how menin upr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858561/ https://ncbi.nlm.nih.gov/pubmed/17766243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609555200 |
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