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A stress-responsive RNA switch regulates VEGF expression

Ligand binding to structural elements in noncoding regions of mRNA modulates gene expression1,2. Ligands such as free metabolites or other small molecules directly bind and induce conformational changes in regulatory RNA elements known as riboswitches1-4. Other types of RNA switches are activated by...

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Autori principali: Ray, Partho Sarothi, Jia, Jie, Yao, Peng, Majumder, Mithu, Hatzoglou, Maria, Fox, Paul L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858559/
https://ncbi.nlm.nih.gov/pubmed/19098893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07598
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