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A stress-responsive RNA switch regulates VEGF expression

Ligand binding to structural elements in noncoding regions of mRNA modulates gene expression1,2. Ligands such as free metabolites or other small molecules directly bind and induce conformational changes in regulatory RNA elements known as riboswitches1-4. Other types of RNA switches are activated by...

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Detalhes bibliográficos
Main Authors: Ray, Partho Sarothi, Jia, Jie, Yao, Peng, Majumder, Mithu, Hatzoglou, Maria, Fox, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858559/
https://ncbi.nlm.nih.gov/pubmed/19098893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07598
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