High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia

Self-renewal is a feature of cancer and can be assessed by cell transplantation into immune-compromised or immune-matched animals. However, studies in zebrafish have been severely limited by lack of these reagents. Here, Myc-induced T-cell acute lymphoblastic leukemias (T-ALLs) have been made in syn...

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Detalhes bibliográficos
Main Authors: Smith, Alexandra C. H., Raimondi, Aubrey R., Salthouse, Chris D., Ignatius, Myron S., Blackburn, Jessica S., Mizgirev, Igor V., Storer, Narie Y., de Jong, Jill L. O., Chen, Aye T., Zhou, Yi, Revskoy, Sergei, Zon, Leonard I., Langenau, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858492/
https://ncbi.nlm.nih.gov/pubmed/20056790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246488
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