Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease

Growth arrest-specific gene 6 (Gas6) is expressed in antigen-presenting cells and endothelial cells (ECs) but not in T cells. When wild-type (WT) or Gas6(−/−) mice received allogeneic non–T cell–depleted bone marrow cells, hepatic graft-versus-host disease (GVHD) was alleviated in Gas6(−/−) recipien...

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Hlavní autoři: Burnier, Laurent, Saller, François, Kadi, Linda, Brisset, Anne C., Sugamele, Rocco, Baudino, Lucie, Bono, Françoise, Herbert, Jean-Marc, Carmeliet, Peter, Schapira, Marc, Izui, Shozo, Angelillo-Scherrer, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858482/
https://ncbi.nlm.nih.gov/pubmed/20139094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-206920
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