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Small Molecule DnaK Modulators Targeting the β-Domain

The molecular chaperone DnaK is essential for the survival of bacterial pathogens in the hostile environment of the host. Hence, it is in principle a promising target for drug design but for which no current inhibitors are available apart from certain antimicrobial peptides. To this end, we have scr...

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Détails bibliographiques
Auteurs principaux: Cellitti, Jason, Zhang, Ziming, Wang, Si, Wu, Bainan, Yuan, Hongbin, Hasegawa, Patty, Guiney, Donald G., Pellecchia, Maurizio
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858402/
https://ncbi.nlm.nih.gov/pubmed/19694756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00869.x
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