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Method for evaluating the potential of (14)C labeled plant polyphenols to cross the blood-brain barrier using accelerator mass spectrometry

Bioactive compounds in botanicals may be beneficial in preventing age-related neurodegenerative diseases, but for many compounds conventional methods may be inadequate to detect if these compounds cross the blood brain barrier or to track the pharmacokinetics in the brain. By combining a number of u...

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Autors principals: Janle, Elsa M, Lila, Mary Ann, Grannan, Michael, Wood, Lauren, Higgins, Aine, Yousef, Gad G, Rogers, Randy B, Kim, Helen, Jackson, George S, Weaver, Connie M
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858353/
https://ncbi.nlm.nih.gov/pubmed/20419067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nimb.2009.10.161
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