Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor

The liver is the most common site of adenocarcinoma metastases, even in patients who initially present with early disease. We postulated that immune-suppressive cells in the liver of tumor-bearing hosts inhibit anti-tumor T cells, thereby accelerating the growth of liver metastases. Using models of...

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Huvudupphovsmän: Connolly, Michael K., Mallen-St. Clair, Jon, Bedrosian, Andrea S., Malhotra, Ashim, Vera, Valery, Ibrahim, Junaid, Henning, Justin, Pachter, H. Leon, Bar-Sagi, Dafna, Frey, Alan B., Miller, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Society for Leukocyte Biology 2010
Ämnen:
Inflammation, Extracellular Mediators, & Effector Molecules
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858308/
https://ncbi.nlm.nih.gov/pubmed/20042467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0909607
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