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Human Papillomavirus E7 Oncoprotein Overrides the Tumor Suppressor Activity of p21(Cip1) in Cervical Carcinogenesis

The E7 oncoprotein of the high-risk human papillomaviruses (HPV) is thought to contribute to cervical carcinogenesis at least in part by abrogating cell cycle regulation. E7 can dysregulate the cell cycle through its interaction with several cellular proteins including the retinoblastoma suppressor...

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Détails bibliographiques
Auteurs principaux: Shin, Myeong-Kyun, Balsitis, Scott, Brake, Tiffany, Lambert, Paul F.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858290/
https://ncbi.nlm.nih.gov/pubmed/19584294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3711
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