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Human Papillomavirus E7 Oncoprotein Overrides the Tumor Suppressor Activity of p21(Cip1) in Cervical Carcinogenesis

The E7 oncoprotein of the high-risk human papillomaviruses (HPV) is thought to contribute to cervical carcinogenesis at least in part by abrogating cell cycle regulation. E7 can dysregulate the cell cycle through its interaction with several cellular proteins including the retinoblastoma suppressor...

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Detalhes bibliográficos
Main Authors: Shin, Myeong-Kyun, Balsitis, Scott, Brake, Tiffany, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858290/
https://ncbi.nlm.nih.gov/pubmed/19584294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3711
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