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Strain background effects and genetic modifiers of hearing in mice

Genetic modifiers can be detected in mice by looking for strain background differences in inheritance or phenotype of a mutation. They can be mapped by analyses of appropriate linkage crosses and congenic lines, and modifier genes of large effect can be identified by positional-candidate gene testin...

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Bibliographic Details
Main Authors: Johnson, Kenneth R., Zheng, Qing Yin, Noben-Trauth, Konrad
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858224/
https://ncbi.nlm.nih.gov/pubmed/16579977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.02.021
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