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Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss
Age-related hearing loss (AHL) in common inbred mouse strains is a genetically complex quantitative trait. We found a synonymous single-nucleotide polymorphism in exon 7 of Cdh23 that shows significant association with AHL and the deafness modifier mdfw (modifer of deafwaddler). The hypomorphic Cdh2...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864026/ https://ncbi.nlm.nih.gov/pubmed/12910270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1226 |
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