Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss

BACKGROUND: Recurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus or to uterine factors that are poorly defined. We tested the hypothesis that abnormal cyclic differentiation of endometrial stro...

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Hlavní autoři: Salker, Madhuri, Teklenburg, Gijs, Molokhia, Mariam, Lavery, Stuart, Trew, Geoffrey, Aojanepong, Tepchongchit, Mardon, Helen J., Lokugamage, Amali U., Rai, Raj, Landles, Christian, Roelen, Bernard A. J., Quenby, Siobhan, Kuijk, Ewart W., Kavelaars, Annemieke, Heijnen, Cobi J., Regan, Lesley, Macklon, Nick S., Brosens, Jan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858209/
https://ncbi.nlm.nih.gov/pubmed/20422017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010287
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