The Hrs/Stam Complex Acts as a Positive and Negative Regulator of RTK Signaling during Drosophila Development

BACKGROUND: Endocytosis is a key regulatory step of diverse signalling pathways, including receptor tyrosine kinase (RTK) signalling. Hrs and Stam constitute the ESCRT-0 complex that controls the initial selection of ubiquitinated proteins, which will subsequently be degraded in lysosomes. It has be...

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Detalhes bibliográficos
Main Authors: Chanut-Delalande, Hélène, Jung, Alain C., Baer, Magdalena M., Lin, Li, Payre, François, Affolter, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858154/
https://ncbi.nlm.nih.gov/pubmed/20422006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010245
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