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Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors

BACKGROUND: Beclin 1, an important autophagy-related protein in human cells, is involved in cell death and cell survival. Beclin 1 mapped to human chromosome 17q21. It is widely expressed in normal mammary epithelial cells. Although down-regulated expression with mono-allelic deletions of beclin 1 g...

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מידע ביבליוגרפי
Main Authors: Li, Zidong, Chen, Bo, Wu, Yiqing, Jin, Feng, Xia, Yongjing, Liu, Xiangjun
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858113/
https://ncbi.nlm.nih.gov/pubmed/20230646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-98
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