Phosphorylation of paxillin at threonine 538 by PKCδ regulates LFA1-mediated adhesion of lymphoid cells

We investigated the PKCδ-mediated phosphorylation of paxillin within its LIM4 domain and the involvement of this phosphorylation in activation of LFA-1 integrins of the Baf3 pro-B lymphocytic cell line. Using phosphorylated-threonine-specific antibodies, phosphorylated amino acid analysis and paxill...

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Detalhes bibliográficos
Main Authors: Romanova, Larisa Y., Holmes, Gibran, Bahte, Svenja K., Kovalchuk, Alexander L., Nelson, Patrick J., Ward, Yvona, Gueler, Faikah, Mushinski, J. Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858022/
https://ncbi.nlm.nih.gov/pubmed/20388733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.060996
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