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NMDA-stimulated ERK1/2 Signaling and the Transcriptional Up-regulation of Plasticity-related Genes are Developmentally Regulated following in vitro Neuronal Maturation

The general features of neuroplasticity are developmentally regulated. Although it has been hypothesized that the loss of plasticity in mature neurons may be due to synaptic saturation and functional reduction of NMDA receptors (NMDAR), the molecular mechanisms remain largely unknown. We examined th...

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Autori principali: Zhou, Xianju, Moon, Changjong, Zheng, Fei, Luo, Yongneng, Soellner, Deborah, Nuñez, Joseph L., Wang, Hongbing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857719/
https://ncbi.nlm.nih.gov/pubmed/19396876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22103
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