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Metabolic catastrophe as a means to cancer cell death

During tumorigenesis, normal growth mechanisms are deregulated and safeguards that eliminate abnormal cells by apoptosis are disabled. Tumor cells must also increase nutrient uptake and angiogenesis to support the upregulation of metabolism necessary for unrestricted growth. In addition, they have t...

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Detalhes bibliográficos
Main Authors: Jin, Shengkan, DiPaola, Robert S., Mathew, Robin, White, Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857576/
https://ncbi.nlm.nih.gov/pubmed/17251378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.03349
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