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Role of Autophagy in Cancer: Management of Metabolic Stress
Human breast, ovarian, and prostate tumors display allelic loss of the essential autophagy gene beclin1 with high frequency, and an increase in the incidence of tumor formation is observed in beclin1(+/−) mutant mice. These findings suggest a role for beclin1 and autophagy in tumor suppression; howe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770734/ https://ncbi.nlm.nih.gov/pubmed/16969128 |
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