Organophosphate Exposure During a Critical Developmental Stage Reprograms Adenylyl Cyclase Signaling in PC12 Cells

Early-life organophosphate (OP) exposures elicit neurobehavioral deficits through mechanisms other than inhibiting cholinesterase. Cell signaling cascades are postulated as critical noncholinesterase targets that mediate both the initial alterations in neurodevelopment as well as subsequent abnormal...

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Hlavní autoři: Adigun, Abayomi A., Ryde, Ian T., Seidler, Frederic J., Slotkin, Theodore A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857560/
https://ncbi.nlm.nih.gov/pubmed/20298678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.03.025
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