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Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

Phosphorothioate oligodeoxynucleotides can activate complement, and experimental murine studies have revealed differential effects upon simultaneous TLR stimulation and complement activation compared with either event alone. We set out to investigate the immune stimulatory effects of CpG 2006 in fre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mangsbo, Sara M., Sanchez, Javier, Anger, Kerstin, Lambris, John D., Ekdahl, Kristina Nilsson, Loskog, Angelica S., Nilsson, Bo, Tötterman, Thomas H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857538/
https://ncbi.nlm.nih.gov/pubmed/19864604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902374
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