Gene expression of PPARγ and PGC-1α in human omental and subcutaneous adipose tissue is related to insulin resistance markers and mediates beneficial effects of physical training

OBJECTIVE: Obesity and type 2 diabetes are reaching epidemic proportions in Western societies and contribute to substantial morbidity and mortality. The PPARγ and PGC-1α system plays an important role in regulating efficient energy utilization and oxidative phosphorylation both of which are decrease...

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Autori principali: Ruschke, Karen, Fishbein, Lauren, Dietrich, Arne, Klöting, Nora, Tönjes, Anke, Oberbach, Andreas, Fasshauer, Mathias, Jenkner, Jost, Schön, Michael R., Stumvoll, Michael, Blüher, Matthias, Mantzoros, Christos S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857401/
https://ncbi.nlm.nih.gov/pubmed/19966034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-09-0767
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