A Yersinia pestis guaBA mutant is attenuated in virulence and provides protection against plague in a mouse model of infection

There is a need to develop effective countermeasures for Yersinia pestis, the etiologic agent of plague and a potential bioterrorism agent. Salmonella and Shigella spp. deleted in the guaBA genes involved in guanine biosynthesis have been shown to be attenuated in vivo. In this study, we sought to d...

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Библиографические подробности
Главные авторы: Oyston, Petra C. F., Mellado-Sanchez, Gabriela, Pasetti, Marcela F., Nataro, James P., Titball, Richard W., Atkins, Helen S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857377/
https://ncbi.nlm.nih.gov/pubmed/20096773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.01.005
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