Ubiquitin Proteasome Dysfunction in Human Hypertrophic and Dilated Cardiomyopathies

BACKGROUND: The ubiquitin proteasome system (UPS) maintains a dynamic equilibrium of proteins and prevents accumulation of damaged and misfolded proteins, yet its role in human cardiac dysfunction is not well understood. The present study evaluated UPS function in human heart failure and hypertrophi...

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Hlavní autoři: Predmore, Jaime M., Wang, Ping, Davis, Frank, Bartolone, Sarah, Westfall, Margaret V., Dyke, David B., Pagani, Francis, Powell, Saul R., Day, Sharlene M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857348/
https://ncbi.nlm.nih.gov/pubmed/20159828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.904557
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