Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

BACKGROUND: Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively controlled with eculizumab. However, lactate dehydrogenase levels remain slightly elevated and haptoglobin levels remain low in some...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hill, Anita, Rother, Russell P., Arnold, Louise, Kelly, Richard, Cullen, Matthew J., Richards, Stephen J., Hillmen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857185/
https://ncbi.nlm.nih.gov/pubmed/20145265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007229
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados