Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

BACKGROUND: Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively controlled with eculizumab. However, lactate dehydrogenase levels remain slightly elevated and haptoglobin levels remain low in some...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hill, Anita, Rother, Russell P., Arnold, Louise, Kelly, Richard, Cullen, Matthew J., Richards, Stephen J., Hillmen, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: Ferrata Storti Foundation 2010
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857185/
https://ncbi.nlm.nih.gov/pubmed/20145265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007229
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים