Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

BACKGROUND: Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively controlled with eculizumab. However, lactate dehydrogenase levels remain slightly elevated and haptoglobin levels remain low in some...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hill, Anita, Rother, Russell P., Arnold, Louise, Kelly, Richard, Cullen, Matthew J., Richards, Stephen J., Hillmen, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857185/
https://ncbi.nlm.nih.gov/pubmed/20145265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007229
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares