Hematopoietic stem cells in co-culture with mesenchymal stromal cells - modeling the niche compartments in vitro

BACKGROUND: Hematopoietic stem cells located in the bone marrow interact with a specific microenvironment referred to as the stem cell niche. Data derived from ex vivo co-culture systems using mesenchymal stromal cells as a feeder cell layer suggest that cell-to-cell contact has a significant impact...

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Autores principales: Jing, Duohui, Fonseca, Ana-Violeta, Alakel, Nael, Fierro, Fernando A., Muller, Katrin, Bornhauser, Martin, Ehninger, Gerhard, Corbeil, Denis, Ordemann, Rainer
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857183/
https://ncbi.nlm.nih.gov/pubmed/20145267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.010736
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