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Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro

BACKGROUND: In the bone marrow mesenchymal stromal cells and osteoblasts form functional niches for hematopoietic stem and progenitor cells. This microenvironment can be partially mimicked using in vitro co-culture systems. In this study, we examined the oxygen tension in three distinct compartments...

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Main Authors: Jing, Duohui, Wobus, Manja, Poitz, David M., Bornhäuser, Martin, Ehninger, Gerhard, Ordemann, Rainer
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291585/
https://ncbi.nlm.nih.gov/pubmed/22058205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050815
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