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Discovery and Characterization of an Amidinotransferase Involved in the Modification of Archaeal tRNA

The presence of the 7-deazaguanosine derivative archaeosine (G(+)) at position 15 in tRNA is one of the diagnostic molecular characteristics of the Archaea. The biosynthesis of this modified nucleoside is especially complex, involving the initial production of 7-cyano-7-deazaguanine (preQ(0)), an ad...

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Detalhes bibliográficos
Main Authors: Phillips, Gabriela, Chikwana, Vimbai M., Maxwell, Adrienne, El-Yacoubi, Basma, Swairjo, Manal A., Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857094/
https://ncbi.nlm.nih.gov/pubmed/20129918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102236
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