Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice

Conversion to glycogen is a major fate of ingested glucose in the body. A rate-limiting enzyme in the synthesis of glycogen is glycogen synthase encoded by two genes, GYS1, expressed in muscle and other tissues, and GYS2, primarily expressed in liver (liver glycogen synthase). Defects in GYS2 cause...

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Main Authors: Irimia, Jose M., Meyer, Catalina M., Peper, Caron L., Zhai, Lanmin, Bock, Cheryl B., Previs, Stephen F., McGuinness, Owen P., DePaoli-Roach, Anna, Roach, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857087/
https://ncbi.nlm.nih.gov/pubmed/20178984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106534
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