Coordinate Down-regulation of Adenylyl Cyclase Isoforms and the Stimulatory G Protein (G(s)) in Intestinal Epithelial Cell Differentiation

The intestinal epithelium is dynamic, with proliferation of undifferentiated crypt cells balanced by terminal differentiation and cell death at the colon surface or small intestinal villus tips. Cyclic AMP, induced by agonists such as prostaglandin E(2) and vasoactive intestinal polypeptide, promote...

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Detalhes bibliográficos
Main Authors: Choi, Lillian J., Jenikova, Gabriela, Hanson, Elaine, Spehlmann, Martina E., Boehling, Nicholas S., Kirstein, Shelli L., Bundey, Richard A., Smith, Jennifer R., Insel, Paul A., Eckmann, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857080/
https://ncbi.nlm.nih.gov/pubmed/20157112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059741
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