Hantavirus Nucleocapsid Protein Has Distinct m(7)G Cap- and RNA-binding Sites

Hantaviruses, members of the Bunyaviridae family, are emerging category A pathogens that carry three negative stranded RNA molecules as their genome. Hantavirus nucleocapsid protein (N) is encoded by the smallest S segment genomic RNA (viral RNA). N specifically binds mRNA caps and requires four nuc...

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Bibliographic Details
Main Authors: Mir, Mohammad A., Sheema, Sheema, Haseeb, Abdul, Haque, Absarul
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857014/
https://ncbi.nlm.nih.gov/pubmed/20164193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102459
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