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Ribosomal protein S19 binding domain provides insights into hantavirus nucleocapsid protein-mediated translation initiation mechanism

The hantaviral zoonotic diseases pose significant threat to human health due to the lack of potential antiviral therapeutics or a vaccine against hantaviruses. Sin Nombre hantavirus nucleocapsid protein (N) augments mRNA translation. N binds to both the mRNA 5′ cap and 40S ribosomal subunit via ribo...

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Detalles Bibliográficos
Publicado en:Biochem J
Main Authors: Ganaie, Safder S, Haque, Absarul, Cheng, Erdong, Bonny, Tania S., Salim, Nilshad N., Mir, Mohammad A
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315616/
https://ncbi.nlm.nih.gov/pubmed/25062117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140449
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