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Using Engineered 2-O-Sulfotransferase to Determine the Activity of Heparan Sulfate C(5)-epimerase and Its Mutants
Heparan sulfate (HS) is involved in essential physiological and pathophysiological functions. HS is a highly sulfated polysaccharide consisting of glucuronic acid (or iduronic acid) linked to glucosamine carrying various sulfo groups. Biosynthesis of HS involves sulfotransferases and an epimerase. T...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856987/ https://ncbi.nlm.nih.gov/pubmed/20118238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081059 |
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