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Interplay between the ubiquitin-proteasome system and autophagy in proteinopathies

Proteinopathies are a family of human disease caused by toxic aggregation-prone proteins and featured by the presence of protein aggregates in the affected cells. The ubiquitin-proteasome system (UPS) and autophagy are two major intracellular protein degradation pathways. The UPS mediates the target...

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Hlavní autoři: Zheng, Qingwen, Li, Jie, Wang, Xuejun
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856956/
https://ncbi.nlm.nih.gov/pubmed/20411034
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