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A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

Lysine acetylation of histones defines the epigenetic status of human embryonic stem cells and orchestrates DNA replication, chromosome condensation, transcription, telomeric silencing, and DNA repair. A detailed mechanistic explanation of these phenomena is impeded by the limited availability of ho...

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Detalhes bibliográficos
Main Authors: Neumann, Heinz, Hancock, Susan M., Buning, Ruth, Routh, Andrew, Chapman, Lynda, Somers, Joanna, Owen-Hughes, Tom, van Noort, John, Rhodes, Daniela, Chin, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856916/
https://ncbi.nlm.nih.gov/pubmed/19818718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.027
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