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pH-dependent self-association of zinc-free Insulin characterized by concentration-gradient static light scattering
Insulin self-association at pH 1.85, 1.95, 3.0, 7.2, 8.0 and 10 was studied via composition gradient light scattering (CG-SLS). At pH 1.95 in acetic acid, insulin was found to exist as a monomer, and in pH 1.85 HCl as a dimer. At pH values of 3.0 – 8.0, the dependence of scattering intensity upon to...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856799/ https://ncbi.nlm.nih.gov/pubmed/20202737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2010.02.002 |
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