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A G Protein-Coupled Receptor is Essential for Schwann Cells to Initiate Myelination

The myelin sheath allows axons to rapidly conduct action potentials in the vertebrate nervous system. Incompletely understood axonal signals activate specific transcription factors, including Oct6 and Krox20, that initiate myelination in Schwann cells. Elevation of cAMP can mimic axonal contact in v...

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書誌詳細
主要な著者: Monk, Kelly R., Naylor, Stephen G., Glenn, Thomas D., Mercurio, Sara, Perlin, Julie R., Dominguez, Claudia, Moens, Cecilia B., Talbot, William S.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856697/
https://ncbi.nlm.nih.gov/pubmed/19745155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1173474
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