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A G Protein-Coupled Receptor is Essential for Schwann Cells to Initiate Myelination
The myelin sheath allows axons to rapidly conduct action potentials in the vertebrate nervous system. Incompletely understood axonal signals activate specific transcription factors, including Oct6 and Krox20, that initiate myelination in Schwann cells. Elevation of cAMP can mimic axonal contact in v...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856697/ https://ncbi.nlm.nih.gov/pubmed/19745155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1173474 |
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