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Matrix Metalloproteinases, T Cell Homing and β-Cell Mass in Type 1 Diabetes

The pathogenesis of type 1 diabetes begins with the activation of autoimmune T killer cells and is followed by their homing into the pancreatic islets. After penetrating the pancreatic islets, T cells directly contact and destroy insulin-producing β cells. This review provides an overview of the dyn...

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Detalhes bibliográficos
Main Authors: Savinov, Alexei Y., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856594/
https://ncbi.nlm.nih.gov/pubmed/19251049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0083-6729(08)00618-3
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