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Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of Progressive Multifocal Leukoencephalopathy

Activation of viral promoter transcription is a crucial event in the life cycle of several viruses. Hypoxia inducible factor-1 alpha (HIF-1α) is an inducible transcription factor whose activity is dependent on environmental conditions, most notably oxygen levels and cellular stress. HIF-1α has been...

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Autors principals: Piña-Oviedo, Sergio, Khalili, Kamel, Del Valle, Luis
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856344/
https://ncbi.nlm.nih.gov/pubmed/19360424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0533-0
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