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p53 Activation: A Case against Sir

The p53 tumor suppressor is a critical transcription factor for controlling cell growth and apoptosis during times of cellular stress. In this issue of Cancer Cell, Lain et al. have used a p53-responsive reporter gene as the readout for screening small-molecule activators of p53 that could potential...

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Detalhes bibliográficos
Main Authors: Brooks, Christopher L., Gu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856338/
https://ncbi.nlm.nih.gov/pubmed/18455119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.04.009
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