The Neurosecretory Vesicle Protein Phogrin Functions as a Phosphatidylinositol Phosphatase to Regulate Insulin Secretion

Phogrin is a transmembrane protein expressed in cells with stimulus-coupled peptide hormone secretion, including pancreatic beta cells, in which it is localized to the membrane of insulin-containing dense-core vesicles. By sequence, phogrin is a member of the family of receptor-like protein-tyrosine...

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Detalles Bibliográficos
Autores principales: Caromile, Leslie A., Oganesian, Anush, Coats, Scott A., Seifert, Ronald A., Bowen-Pope, Daniel F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Enzymology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856256/
https://ncbi.nlm.nih.gov/pubmed/20097759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066563
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