Long-Lived, High-Strength States of ICAM-1 Bonds to β(2) Integrin, I: Lifetimes of Bonds to Recombinant α(L)β(2) Under Force

Using single-molecule force spectroscopy to probe ICAM-1 interactions with recombinant α(L)β(2) immobilized on microspheres and β(2) integrin on neutrophils, we quantified an impressive hierarchy of long-lived, high-strength states of the integrin bond, which start from basal levels with integrin ac...

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Hlavní autoři: Evans, Evan, Kinoshita, Koji, Simon, Scott, Leung, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Cellular Biophysics and Electrophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856188/
https://ncbi.nlm.nih.gov/pubmed/20409464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.067
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