Integrin α4β1 signaling is required for lymphangiogenesis and tumor metastasis

Recent studies have shown that lymphangiogenesis, or the growth of lymphatic vessels, at the periphery of tumors promotes tumor metastasis to lymph nodes. We show here that the fibronectin-binding integrin α4β1 and its ligand fibronectin are novel functional markers of proliferative lymphatic endoth...

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Autors principals: Garmy-Susini, Barbara, Avraamides, Christie J., Schmid, Michael C., Foubert, Philippe, Ellies, Lesley G., Barnes, Leo, Feral, Chloe, Papayannopoulou, Thalia, Lowy, Andrew, Blair, Sarah L., Cheresh, David, Ginsberg, Mark, Varner, Judith A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856096/
https://ncbi.nlm.nih.gov/pubmed/20388801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3761
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