Intracellular and plasma steady-state pharmacokinetics of raltegravir, darunavir, etravirine and ritonavir in heavily pre-treated HIV-infected patients

AIM: To study the steady-state plasma and intracellular pharmacokinetics of raltegravir, etravirine, darunavir and ritonavir in heavily pre-treated patients. METHODS: Patients on a salvage regimen containing raltegravir, etravirine, darunavir and ritonavir were eligible for inclusion. During a 12 h...

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Autores principales: ter Heine, Rob, Mulder, Jan Willem, van Gorp, Eric C M, Wagenaar, Jiri F P, Beijnen, Jos H, Huitema, Alwin D R
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2010
Materias:
Pharmacokinetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856048/
https://ncbi.nlm.nih.gov/pubmed/20573083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03634.x
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