Development and validation of a population pharmacokinetic model for ritonavir used as a booster or as an antiviral agent in HIV-1-infected patients

AIMS: The aim of this study was to develop and validate a population pharmacokinetic model of ritonavir, used as an antiviral agent or as a booster, in a large patient population and to identify factors influencing its pharmacokinetics. METHODS: Ambulatory HIV-1-infected patients from the outpatient...

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Detalhes bibliográficos
Main Authors: Kappelhoff, Bregt S, Huitema, Alwin D R, Crommentuyn, Kristel M L, Mulder, Jan W, Meenhorst, Pieter L, van Gorp, Eric C M, Mairuhu, Albert T A, Beijnen, Jos H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884743/
https://ncbi.nlm.nih.gov/pubmed/15676039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02241.x
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