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Effect of 4-Aminopyridine on Action Potential Parameters in Isolated Dog Purkinje Fibers
INTRODUCTION: 4-Aminopyridine (fampridine), a potassium channel blocker, has demonstrated efficacy in improving lower extremity strength and walking speed in patients with multiple sclerosis. Since in vitro electrophysiologic studies are recommended for evaluating a drug's potential to prolong...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Inc
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855834/ https://ncbi.nlm.nih.gov/pubmed/20428229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2009.00027.x |
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