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Prostaglandin E2 Promotes Lung Cancer Cell Migration Via EP4-βArrestin1-c-Src Signalsome

Many human cancers express elevated levels of cyclooxygenase-2 (COX-2), an enzyme responsible for the biosynthesis of prostaglandins. Available clinical data establish a protective effect of COX-2 inhibition on human cancer progression. However, despite these encouraging outcomes, the appearance of...

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Autori principali: Kim, Jae Il, Lakshmikanthan, Vijayabaskar, Frilot, Nicole, Daaka, Yehia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855782/
https://ncbi.nlm.nih.gov/pubmed/20353998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0511
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