Inhibition of Focal Adhesion Kinase Decreases Tumor Growth in Human Neuroblastoma

Neuroblastoma is the most common extracranial solid tumor of childhood. Focal adhesion kinase (FAK) is an intracellular kinase that regulates both cellular adhesion and apoptosis. FAK is overexpressed in a number of human tumors including neuroblastoma. Previously, we have shown that the MYCN oncoge...

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Hauptverfasser: Beierle, Elizabeth A., Ma, Xiaojie, Stewart, Jerry, Nyberg, Carl, Trujillo, Angelica, Cance, William G., Golubovskaya, Vita M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855768/
https://ncbi.nlm.nih.gov/pubmed/20160475
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